GenomicsbioRxivPreprint
A Polygenic Quincunx
The paper models polygenic risk as a branching tree where each SNP adds a random walk step, showing that more SNPs increase risk dispersion and potential clinical benefit.
DOI 10.1101/2023.07.18.549486
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The paper models polygenic risk as a branching tree where each SNP adds a random walk step, showing that more SNPs increase risk dispersion and potential clinical benefit.