William A. Cresko

Functionally convergent anti-predator morphologies arise through divergent cellular strategies in Daphnia

This study investigates how Daphnia lumholtzi develops head and tailspines in response to predator cues, revealing a sustained hyperplasia mechanism distinct from other species.

Lineage-specific change in craniofacial genetic networks of syngnathid fishes revealed by integrating multiomics across fishes

The paper investigates craniofacial genetic network evolution in syngnathid fishes using multiomics data, finding conserved core networks with localized changes contributing to morphological diversity.

Non-genetic inheritance of induced defense morphologies across multiple unexposed generations of Daphnia lumholtzi

The paper shows predator-induced body shape changes in Daphnia lumholtzi persist across multiple unexposed generations, demonstrating non-genetic inheritance of phenotypes.

Genome-wide Analysis Reveals High Genomic Diversity and Panmixia in Bay Pipefish (Syngnathus leptorhynchus) from Coos Bay, Oregon

This study uses RAD-seq to analyze genomic diversity and population structure in bay pipefish, finding high diversity and panmixia across two locations in Coos Bay.

Spontaneous mutant in threespine stickleback connects endosome trafficking disorders and inflammatory bowel diseases via changes in the gut microbiome

The paper uses a mutant fish model to show endosome trafficking disorders link to gut microbiome changes and inflammatory bowel disease.

Quantitative Genetics of Microbiome Mediated Traits

The paper extends quantitative genetic theory to include host-associated microbes as factors influencing phenotypic variation and demonstrates how microbiome-mediated responses to selection can arise from various transmission modes.

Single Cell Sequencing Provides Clues about the Developmental Genetic Basis of Evolutionary Adaptations in Syngnathid Fishes

The paper uses single-cell RNA sequencing to analyze developmental genetic changes in Gulf pipefish embryos, identifying cell types and gene networks associated with evolutionary traits like toothlessness and dermal armor.

Improvements to the Gulf Pipefish Syngnathus scovelli Genome

The paper improves the genome assembly and annotation of the Gulf pipefish Syngnathus scovelli using long-read and Hi-C data, resulting in a more contiguous and accurately annotated genome.

Leafy and Weedy Seadragon Genomes Connect Genic and Repetitive DNA Features to the Extravagant Biology of Syngnathid Fishes

This study presents chromosome-scale genomes for leafy and weedy seadragons, identifying genomic features linked to their unique biology and evolutionary traits.

Single cell Iso-Sequencing enables rapid genome annotation for scRNAseq analysis

The paper demonstrates that combining single cell isoform sequencing with scRNAseq improves 3' UTR annotations and enhances gene identification in stickleback fish.

QTL mapping of intestinal neutrophil variation and inflammation between threespine stickleback populations reveals links to neurodegenerative disease

The paper maps QTLs for intestinal neutrophil variation and inflammation in stickleback populations, linking them to neurodegenerative disease genes.