Systems BiologyScientific ReportsPeer-reviewed
Regulation of the MAPK/ERK system: a computational rule-based model
Paweł Kocieniewski, Tomasz Lipniacki
The paper develops a rule-based computational model of the MAPK/ERK pathway to account for isoform-specific regulation and interactions, revealing how differential RAF-14-3-3 interactions influence signaling behavior.
DOI 10.1038/s41598-026-44353-3