AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fateand controls lymphangiogenesis
Xiaojie Yang, Jun‐Dae Kim, Kelvin Chan, Qilin Gu, Jonathan W. Astin, Philip S. Crosier, Pengchun Yu, Stanley G. Rockson, Hong Chen, Longhou Fang
This study identifies the AIBP-CAV1-VEGFR3 axis as a regulator of lymphangiogenesis, showing that AIBP-mediated cholesterol efflux enhances VEGFC-driven lymphatic vessel formation.
bioRxiv · Oct 16, 2020 · PreprintDevelopmental Biology