Small molecules reveal differential shifts in stability and protein binding for G-quadruplex RNA
Justin G. Martyr, Martina Zafferani, Morgan A. Bailey, Marek D. Zorawski, Nadeska I. Montalvan, Dhanasheel Muralidharan, Michael C. Fitzgerald, Amanda E. Hargrove
This paper investigates how small molecules affect RNA G-quadruplex stability and protein binding, revealing bidirectional impacts and specific protein interactions.
bioRxiv · Feb 10, 2025 · PreprintBiochemistry