The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin
Irina S. Abaeva, Alexander G. Bulakhov, Christopher U.T. Hellen, Tatyana V. Pestova
The paper investigates how TCF25 imposes K48-specificity on Listerin-mediated ubiquitination by interacting with the RING domain and orienting the acceptor ubiquitin.
Genes & Development · May 1, 2025Peer-reviewedMolecular Biology