Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase
Cédric Giaccherini, Sarah Scaglione, Stéphane Coulon, Pierre-Marie Dehé, Pierre-Henri L. Gaillard
The paper identifies phosphorylation sites and SUMO-binding motifs in Eme1 that regulate Mus81-Eme1 endonuclease activity, essential for cell survival in the absence of Rqh1BLM.
PLoS Genetics · Apr 22, 2022Peer-reviewedMolecular Biology