Liang Chen

Using the simple telegraph model to decipher transcriptional burst regulation across genome-wide data

The paper uses a simplified telegraph model to analyze transcriptional burst regulation in scRNA-seq and smFISH data, revealing key regulatory patterns in mouse and human tissues.

Multi-omics reveals lipid metabolism, mitochondrial and extracellular matrix dysregulation of diabetic cardiomyopathy in the human heart

This study uses multi-omics data to identify metabolic, mitochondrial, and extracellular matrix dysregulation in diabetic cardiomyopathy.