Author

Guozhi Jiang

Sun Yat-sen UniversityORCID 0000-0002-2795-714XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Feng JiaoiD· 2 shared Jianshe Yu· 2 shared Liang CheniD· 2 shared Sijia Fang· 2 shared Yueheng WuiD· 2 shared Yuwen WuiD· 2 shared Amy B. GoodaleiD· 1 shared Andrea O. Y. LukiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Feng JiaoORCID

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5 papers

Recent·Most cited

Molecular BiologyiSciencePeer-reviewedAug 21, 2026

Using the simple telegraph model to decipher transcriptional burst regulation across genome-wide data

Liang Chen, Yuwen Wu, Chengkai Yang…·Feng Jiao

The paper uses a simplified telegraph model to analyze transcriptional burst regulation in scRNA-seq and smFISH data, revealing key regulatory patterns in mouse and human tissues.

DOI 10.1016/j.isci.2026.117127

mousehuman

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BioinformaticsbioRxivPreprintAug 21, 2025

Multi-omics reveals lipid metabolism, mitochondrial and extracellular matrix dysregulation of diabetic cardiomyopathy in the human heart

Qiuhan Lu, Shulin Tang, Yuwen Wu…·Guozhi Jiang

This study uses multi-omics data to identify metabolic, mitochondrial, and extracellular matrix dysregulation in diabetic cardiomyopathy.

DOI 10.1101/2025.08.21.671651

humanbulk RNA-seq

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Genetic & Genomic MedicineDiabetologiaPeer-reviewedFeb 19, 2024

Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits

Jianxin Zhen, Yuqin Gu, Piao Wang…·SiYang Maggie Liu

This study identifies four genetic loci associated with gestational diabetes risk and 31 loci linked to glycaemic traits in 30,699 Chinese pregnant women, with MTNR1B showing the strongest association.

42 citationstop 1%

humanwhole-genome sequencing

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GeneticsNaturePeer-reviewedMay 6, 2020

Identification of type 2 diabetes loci in 433,540 East Asian individuals

Cassandra Nichole Spracklen, Momoko Horikoshi, Young Jin Kim…·Kyong Soo Park

This paper identifies 56 new type 2 diabetes loci in 433,540 East Asian individuals through a meta-analysis of GWAS data.

442 citationstop 1%

humanGWAS summary statistics

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GenomicsNature GeneticsPeer-reviewedOct 30, 2017

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland…·Aviad Tsherniak

The paper develops CERES, a computational method to correct copy-number effects in CRISPR-Cas9 essentiality screens, improving specificity in cancer cell line studies.

1,951 citationstop 1%

humanCRISPR screen

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