Author

Maegan V. Harden

Broad InstituteORCID 0000-0002-3607-6416Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:batch correction / integration· 1 Research Focus:deconvolution· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Gail Pairitz JarvikiD· 3 shared Adam Gordon· 2 shared Adithya BalasubramanianiD· 2 shared Christie Kovar· 2 shared Chunhua WengiD· 2 shared Cynthia A. ProwsiD· 2 shared David R. CrossliniD· 2 shared David R. MurdockiD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Gail Pairitz JarvikORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations

Niall J. Lennon, Leah Claire Kottyan, C. Kachulis, Noura S. Abul‐Husn, Josh Arias, Gillian M. Belbin, Jennifer Elizabeth Below, Sonja I. Berndt, Wendy K. Chung, James J. Cimino, Ellen Wright Clayton, John J. Connolly, David R. Crosslin, Ozan Dikilitas, Digna R. Velez Edwards, , Eimear E. Kenny

The paper selects and validates ten polygenic risk scores for clinical use in diverse populations, focusing on chronic diseases and addressing disparities in predictive performance.

medRxiv · May 25, 2023 · PreprintGenetic & Genomic Medicine

Genetic Sex Validation for Sample Tracking in Clinical Testing

Hai Hu, Viktoriya Korchina, Hana Zouk, Maegan V. Harden, David R. Murdock, Alyssa Macbeth, Steven M. Harrison, Niall J. Lennon, Christie Kovar, Adithya Balasubramanian, Lan Zhang, Gauthami Chandanavelli, Divya Pasham, Robb K. Rowley, Ken Wiley, , Donna Marie Muzny

The paper validates genetic sex using a 96-SNP PCR panel to track samples in clinical testing and identify inconsistencies.

bioRxiv · Dec 13, 2021 · PreprintGenomics

Neptune: An environment for the delivery of genomic medicine

Eric Venner, Victoria Yi, David R. Murdock, Sara E. Kalla, Tsung-Jung Wu, Aniko Sabo, Shoudong Li, Qingchang Meng, Tian Xia, Mullai Murugan, Michelle L. Cohen, Christie Kovar, Wei‐Qi Wei, Wendy K. Chung, Chunhua Weng, , Andrea L. Hartzler

Neptune delivers structured genomic data to EHR systems through customizable reports and variant reanalysis, supporting over 15,000 clinical reports.

Genetics in Medicine · Jul 13, 2021Peer-reviewedBioinformatics