Bahareh Dabirmanesh

Deciphering Novel Transcriptional Wiring in Colorectal Cancer: An Integrative Bioinformatic and Experimental Study

This study identifies core genes and hub regulators in colorectal cancer using transcriptomic analysis and CRISPR screening, showing melatonin's effects on cell cycle and viability.

Absence of 8-HDF and MTHF Antenna Chromophore Binding in ErCRY4a Suggests a Possible Flavin-Only Cofactor State: Insights from Biochemical and Computational Analyses

The paper investigates whether ErCRY4a binds 8-HDF or MTHF and finds no evidence of binding, suggesting it may function with only FAD as a cofactor.

Computational analysis of transition temperatures (Tts) of proteins fused to elastin-like polypeptide (ELP): deep fake evaluation of proteins, linkers, and trailers features

The paper presents two models for predicting the phase transition temperature (Tt) of Elastin-like polypeptides (ELPs) fused to proteins, linkers, and trailers, achieving high accuracy with R2=99% and 96%, and uses AI to generate fake proteins for validation.