Author

Bernard Conrad

ORCID 0000-0002-3662-9041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2

Frequent Co-Authors

Christian IseliiD· 2 shared Magnus Pirovino· 2 shared Joseph Alphonsus CurraniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersEcology

Christian IseliORCID

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2 papers

Recent·Most cited

EcologybioRxivPreprintAug 5, 2026

A minimal model of stable autocatalytic RNA-replication through integration of replication, molecular regulation, and energy conversion

Bernard Conrad, Christian Iseli, Magnus Pirovino

This paper develops a minimal mathematical model showing how ATP-dependent allosteric regulation stabilizes RNA replication by taming parasitic mutants through hyperparasitic binding and evolutionary transitions in control and energy conversion.

DOI 10.64898/2026.07.25.740712

statistical model

Evolutionary BiologyPLoS Computational BiologyPeer-reviewedJan 3, 2025

Biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks: degenerating parasite-specific hyperparasite catalysts confer parasite resistance and herald the birth of molecular immunity

Magnus Pirovino, Christian Iseli, Joseph Alphonsus Curran, Bernard Conrad

The paper develops a biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks, showing that hyperparasites confer parasite resistance and explain the origin of molecular immunity.

4 citations

statistical model