Cystic fibrosis transmembrane conductance regulator (CFTR) downregulates the excitability of deep pyramidal neurons in the rodent cortex
Zongyue Cheng, Xuan Sun, Xing Wang, Fei Luo, Hsiao Chang Chan, Wen‐Biao Gan, Bao‐Ming Li
This study shows CFTR modulates neuronal excitability and synaptic transmission in the rodent cortex by altering chloride homeostasis and action potential activity.
bioRxiv · Aug 29, 2023 · PreprintNeuroscience