BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewed
MACMIC Reveals Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes
Guangyu Wang, Bo Xia, Man Zhou…·Kaifu Chen
The paper introduces MACMIC, a method to identify feature pairs with maximal colocalization and minimal correlation, revealing CTCF's dual role in regulating cell identity genes through epigenetic mechanisms.