Author

Bo Xia

Houston MethodistORCID 0000-0003-1983-0015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Kaifu CheniD· 2 shared Arulsamy KulandaisamyiD· 1 shared Dongyu ZhaoiD· 1 shared Guangyu WangiD· 1 shared Hong CheniD· 1 shared Jie LviD· 1 shared John P. CookeiD· 1 shared Lili ZhangiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Kaifu ChenORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 27, 2024

Machine Learning Uncovers Vascular Endothelial Cell Identity Genes by Expression Regulation Features in Single Cells

Arulsamy Kulandaisamy, Bo Xia, Hong Chen…·Kaifu Chen

SCIG identifies cell identity genes using genetic sequence signatures and single-cell RNA-seq data without comparing to other cells, revealing master transcription factors and the role of tissue microenvironment.

2 citations

humanscRNA-seq

𝕏 PostBluesky

BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewedFeb 1, 2021

MACMIC Reveals Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes

Guangyu Wang, Bo Xia, Man Zhou…·Kaifu Chen

The paper introduces MACMIC, a method to identify feature pairs with maximal colocalization and minimal correlation, revealing CTCF's dual role in regulating cell identity genes through epigenetic mechanisms.

8 citations

humanChIP-seq

𝕏 PostBluesky