Author

Xi Zhou

Chinese Academy of SciencesORCID 0000-0002-3846-5079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:graph neural network· 1 Organism:human· 1

Frequent Co-Authors

Bo-Wei ZhaoiD· 1 shared Dan LiuiD· 1 shared Deyu Xu· 1 shared Jing LouiD· 1 shared Libo ZhangiD· 1 shared Lun HuiD· 1 shared Pengwei HuiD· 1 shared Xiaobei Xiong· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Bo-Wei ZhaoORCID

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2 papers

Recent·Most cited

CellPulse: A Foundation Model of Coordinated Gene Dynamics Simulating Viral Infectious Diseases

Dan Liu, Xiaoxu Zhu, Libo Zhang, Deyu Xu, Jing Lou, Xiaobei Xiong, Yukun Ren, Y N Wu, Xi Zhou

CellPulse is a foundation model trained on viral infection data to simulate coordinated gene dynamics, enabling virus classification and drug discovery through host transcriptional signatures.

bioRxiv · Apr 24, 2026 · PreprintBioinformatics

A geometric deep learning framework for drug repositioning over heterogeneous information networks

Bo-Wei Zhao, Xiaorui Su, Pengwei Hu, Yu-Peng Ma, Xi Zhou, Lun Hu

This paper introduces a geometric deep learning framework for drug repositioning that leverages heterogeneous information networks to predict drug-disease associations.

Briefings in Bioinformatics · Aug 24, 2022Peer-reviewedBioinformatics