Improving GWAS performance in underrepresented groups by appropriate modeling of genetics, environment, and sociocultural factors
Chelsea C. Cataldo‐Ramirez, Meng Hsuan Lin, Aislinn Mcmahon, Christopher R. Gignoux, Timothy D. Weaver, Brenna M. Henn
This paper improves GWAS performance in underrepresented groups by reassigning ambiguous ethnicity codes, using ancestry-matched imputation panels, and incorporating environmental covariates.
bioRxiv · Oct 28, 2024 · PreprintGenetics