Harnessing the Power of Single-Cell Large Language Models with Parameter Efficient Fine-Tuning using scPEFT
Fei He, Ruixin Fei, Jordan Edward Krull…·Dong He Xu
This paper introduces scPEFT, a parameter-efficient fine-tuning framework for scLLMs that improves task adaptation with reduced computational costs and enhances performance in disease-specific and cross-species analyses.