Endurance exercise remodels pulmonary vein sleeve myocytes and promotes a proarrhythmic atrial substrate
Luca Soattin, Leila Topál, Roman Tikhomirov, Daniele Lagomarsino-Oneto, Sami Al-Othman, Angela W C Lee, Sushant Saluja, Tibor Hornyik, Zoltán Husti, Jenő Antal Pintér, Aiman Saleh A. Mohammed, Matthew Smith, Alice J. Francis, Megan K. McKie, Eleonora Torre, , Alicia D’Souza
This study shows endurance exercise increases proarrhythmic remodeling in pulmonary vein sleeve myocytes and the PV-LA junction, contributing to atrial fibrillation susceptibility in athletes.
European Heart Journal · Apr 24, 2026Peer-reviewedPhysiology