Author

M. Blake Evans

National Institutes of HealthORCID 0000-0002-4144-7891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexandra M. PochiD· 1 shared Briana YoungiD· 1 shared Dawn E. Watkins‐ChowiD· 1 shared Donald F. ConradiD· 1 shared Kenneth Ivan AstoniD· 1 shared Marja G. BrolinsoniD· 1 shared Rachel L. CosbyiD· 1 shared Sherry RallsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Alexandra M. PochORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

PRDM9-mediated meiotic hotspot specification is constrained in humans despite extensive sequence diversity

Rachel L. Cosby, Marja G. Brolinson, Alexandra M. Poch, M. Blake Evans, Dawn E. Watkins‐Chow, Briana Young, Sherry Ralls, Veronica Gomez‐Lobo, Kenneth Ivan Aston, Donald F. Conrad, Todd S. Macfarlan

The paper functionally characterizes human PRDM9 alleles to show that despite sequence diversity, most alleles function similarly, while rare variants show extreme DNA binding effects.

bioRxiv · Sep 15, 2026 · PreprintGenomics