Systems BiologybioRxivPreprint
Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington’s disease
Seth A. Ament, Jocelynn R. Pearl, Robert M. Bragg…·Nathan D. Price
The paper builds genome-scale transcriptional regulatory networks for mouse and human striatum, identifying SMAD3 as a key regulator in Huntington’s disease.