BioinformaticsbioRxivPreprint
When the Background Matters: Topic-Dependent reference lists in GWAS and Exome Analyses
Brian Timoney, Paolo Guasoni, Komal Zade…·Daniela Tropea
The paper shows that using mismatched genome or exome backgrounds in GO analysis affects significance and introduces annotation bias, with practical implications for GWAS and WES studies.
DOI 10.64898/2026.08.14.744838