The cytidine deaminase APOBEC3G drives cancer mutagenesis and clonal evolution in bladder cancer
Weisi Liu, Kevin P. Newhall, Francesca Khani, LaMont J. Barlow, Duy D. Nguyen, Lilly ChunHong Gu, Kenneth Wha Eng, Bhavneet Bhinder, Manik Uppal, Charlotte Récapet, Andrea Sboner, Susan R. Ross, Olivier Elemento, Linda Chelico, Bishoy M. Faltas
This study shows that APOBEC3G drives mutagenesis and clonal evolution in bladder cancer, contributing to mutational profiles in multiple cancer types.
bioRxiv · Sep 5, 2022 · PreprintGenomics