Author

Duy D. Nguyen

Weill Cornell MedicineORCID 0000-0002-7343-8017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bishoy M. FaltasiD· 3 shared Olivier ElementoiD· 3 shared Weisi LiuiD· 3 shared Andrea SboneriD· 2 shared Bhavneet BhinderiD· 2 shared Linda ChelicoiD· 2 shared Nicolas RobineiD· 2 shared William F. HooperiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersGenomics

Bishoy M. FaltasORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 21, 2025

APOBEC3A-Induced DNA Damage Drives Polymerase Theta Dependency and Synthetic Lethality in Cancer

Abhishek Bose, Weisi Liu, Paul Yoo…·Bishoy M. Faltas

This study identifies TMEJ as the main repair pathway for APOBEC3A-induced DSBs and shows Polθ inhibition causes synthetic lethality in cancer cells with APOBEC3A activity.

1 citation

humanwhole-genome sequencing

GenomicsbioRxivPreprintMay 7, 2023

The Interplay between Mutagenesis and Extrachromosomal DNA Shapes Urothelial Cancer Evolution

Duy D. Nguyen, William F. Hooper, Timothy R. Chu…·Bishoy M. Faltas

This study examines how mutagenesis and extrachromosomal DNA contribute to urothelial cancer evolution, revealing clonal APOBEC3 mutations and chemotherapy-induced mutational bursts within ecDNA.

2 citations

humanwhole-genome sequencing

GenomicsbioRxivPreprintSep 5, 2022

The cytidine deaminase APOBEC3G drives cancer mutagenesis and clonal evolution in bladder cancer

Weisi Liu, Kevin P. Newhall, Francesca Khani…·Bishoy M. Faltas

This study shows that APOBEC3G drives mutagenesis and clonal evolution in bladder cancer, contributing to mutational profiles in multiple cancer types.

3 citations

mousehuman