ERBB4 coordinates fibroblast and myeloid cell function during neonatal cardiac regeneration
Siel Van den Bogaert, Sander Eens, Céline Civati, E Van Den Bogaert, Bo Goovaerts, Julie M. T. Cools, Vincent F. M. Segers, Gilles W. De Keulenaer
This study investigates the role of ERBB4 in fibroblasts and myeloid cells during neonatal cardiac regeneration after myocardial infarction, finding that fibroblast-specific deletion modestly impairs scar resolution while myeloid-specific deletion increases initial injury response but not long-term regeneration.
bioRxiv · Aug 4, 2026 · PreprintPhysiology