Dermaseptin DMS-DA6, a promising alternative to conventional antibiotic in the treatment of N. brasiliensis induced actinomycetoma
Constance Auvynet, Duarte-Mata Diana Ivonne, Anna Velia Vázquez-Marmolejo, Estefanía Alemán-Navarro, Christophe Piesse, Yvonne Rosenstein, Mario Cesar Salinas-Carmona
This study compares the efficacy of the host defense peptide DMS-DA6 with the antibiotic linezolid in treating N. brasiliensis-induced actinomycetoma in mice, finding DMS-DA6 more effective at lower doses and fewer injections.
bioRxiv · Jun 16, 2025 · PreprintMicrobiology