A computational model reveals that spatial localization of cancer stem cells increases radioresistance in tumorspheres
Jerónimo Fotinós, Carlos Alberto Condat, Lucas Barberis
This paper shows that cancer stem cells in tumorspheres are more radioresistant due to their spatial localization in hypoxic regions, which protects them from radiation.
bioRxiv · May 12, 2026 · PreprintCancer Biology