Author

Harvey Jia Wei Koh

Monash UniversityORCID 0000-0002-4304-2783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1

Frequent Co-Authors

Anh T. N. NguyeniD· 1 shared Daniel Francis SchmidtiD· 1 shared Geoffrey I. WebbiD· 1 shared Huan Yee KohiD· 1 shared Johan BarthélemyiD· 1 shared Lauren Therese MayiD· 1 shared Shirui PaniD· 1 shared Vivek NaranbhaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Anh T. N. NguyenORCID

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1 paper

Recent·Most cited

Bioactivity foundation model for hit identification and hit-to-lead optimization from sequence data

Huan Yee Koh, Harvey Jia Wei Koh, Yizhen Zheng, Vivek Naranbhai, Daniel Francis Schmidt, Johan Barthélemy, Ying-Ja Chen, Anh T. N. Nguyen, Shirui Pan, Lauren Therese May, Geoffrey I. Webb

PSICHIC+ is a bioactivity foundation model that predicts binding affinities from sequence data, improving hit identification and hit-to-lead optimization using heterogeneous bioactivity data.

bioRxiv · Oct 31, 2026 · PreprintBioinformatics