BioinformaticsbioRxivPreprint
eSPRESSO: a spatial self-organizing-map clustering method for single-cell transcriptomes of various tissue structures using graph-based networks
Tomoya Mori, Toshiro Takase, Kuan-Chun Lan…·Wataru Fujibuchi
eSPRESSO reconstructs 3D tissue structures from single-cell transcriptomes using stochastic-SOM clustering and MCMC optimization, achieving high reproducibility in multiple tissues and revealing spatial discriminator genes.