GeneticsAnnals of the Rheumatic DiseasesPeer-reviewed
Multi-disease associated risk locus in IL6 represses the anti-inflammatory gene GPNMB through chromatin looping and recruiting MEF2-HDAC complex
The paper identifies a risk locus in IL6 that represses GPNMB via chromatin looping and MEF2-HDAC complex recruitment, linking it to disease susceptibility and immune responses.
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