Targeted Tshz3 deletion in corticostriatal circuit components segregates core autistic behaviors
Xavier Caubit, Paolo Gubellini, Pierre L. Roubertoux, Michèle Carlier, Jordan Molitor, Dorian Chabbert, Mehdi Metwaly, Pascal Salin, Ahmed Fatmi, Yasmine Belaïdouni, Lucie Brosse, Lydia Kerkerian‐Le Goff, Laurent Fasano
This study shows that deleting Tshz3 in specific brain cells affects different autism-related behaviors, highlighting a role for corticostriatal circuits in ASD.
Translational Psychiatry · Mar 15, 2022Peer-reviewedNeuroscience