Author

Candace Bavette Mainor

MedStar Georgetown University HospitalORCID 0000-0002-4431-7101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adam NelsoniD· 1 shared Arielle Lutterman HeekeiD· 1 shared Claudine J. IsaacsiD· 1 shared Edward T. RichardsoniD· 1 shared Filipa C. LynceiD· 1 shared Geoffrey Ira ShapiroiD· 1 shared Hongkun Wang· 1 shared Jane E. Staunton· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam NelsonORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 18, 2026

TALAVE in Breast Cancer: BRCA1/2 Mutation-Dependent Immune Remodeling after PARP Inhibition with Limited Checkpoint Engagement

Filipa C. Lynce, Kaoru Shimada, Claudine J. Isaacs…·Jennifer L. Guerriero

The paper shows BRCA-mutant breast cancers respond to PARP inhibitors with immune remodeling, but PD-L1 blockade is ineffective due to spatial separation of PD-L1+ cells and PD-1+ T cells.

DOI 10.64898/2026.09.17.752386

humanbulk RNA-seq