Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels
José G. Munguia-López, Sangeeth Pillai, Yuli Zhang, Amatzia Gantz, Dimitria Bonizol Camasão, Showan N. Nazhat, Joseph Matthew Kinsella, Simon D. Tran
This study evaluates AG-based hydrogels for expanding human salivary gland spheroids, finding AGHA gels support larger, viable, and functionally active spheroids with sustained protein expression.
International Journal of Oral Science · May 9, 2025Peer-reviewedBioengineering