Application of class-balancing algorithms to diverse plasma metabolomics datasets using brain tumor as an example
Adrian Godlewski, Krzysztof Sołowiej, Patrycja Mojsak, Joanna Godzień, Julia Siemińska, Adam Jacek Kretowski, Tomasz Łysoń, Michał Jan Burdukiewicz, Karol Adam Kamiński, Michał Ciborowski
This study evaluates class-balancing algorithms on metabolomics datasets from brain tumor patients and controls, finding that undersampling improves model performance while oversampling risks overfitting.
bioRxiv · Jul 7, 2026 · PreprintBioinformatics