Anastasia Emmanouilidou

The paper identifies genetic variants near SLC2A2 that influence glycemic response to glimepiride in type 2 diabetes patients.

This study uses long-read sequencing to analyze CRISPR-Cas9 editing outcomes and mosaicism in zebrafish, revealing genetic mosaicism in founder fish and its inheritance to offspring.

The paper introduces Kita as a target for CRISPR/Cas9 screens in zebrafish larvae to improve the reliability and efficiency of genetic screens for complex traits.

This study shows CRISPR-Cas9 induces structural variants and off-target mutations in zebrafish that persist through generations.

The paper introduces amplification-free long-read sequencing protocols to detect CRISPR-Cas9 off-target binding sites, identifying many previously undetected sites that are not predicted by existing software.

The paper uses a CRISPR/Cas9-based approach in zebrafish to identify genes affecting heart rate variability and confirms the role of known genes while highlighting a novel gene.

The paper develops a zebrafish pipeline to study dyslipidemia and atherosclerosis, identifying potential causal genes and showing drug effects.