Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS.
Febe Ferro, C. Roland Wolf, Christopher M. Henstridge, Francisco Iñesta-Vaquera
The paper develops novel in vivo TDP-43 stress reporter models to identify early biomarkers for ALS, showing tissue-specific activation in the cerebellum before clinical signs appear.
Open Biology · Oct 1, 2024Peer-reviewedNeuroscience