Trends Assessment of the Genetic Mutation Induced Protein-Protein Interaction Variation via Protein Large Language Driven Method
Zhejun Kuang, Yunkai Li, Zhe Liu, Jian Ming Zhao, Lijuan Shi, Akira-Kawai, Han Wang
This paper introduces TAPPI, a deep learning framework that assesses trends in protein-protein interaction variations caused by genetic mutations, achieving state-of-the-art performance and biological relevance.
bioRxiv · May 23, 2025 · PreprintBioinformatics