Systems BiologyJournal of Theoretical BiologyPeer-reviewed
Age and Generation-Based Model of Metastatic Cancer: From Micrometastases to Macrometastases
P.N. Gavriliadis, Georgios Lolas, Themis Matsoukas
The paper develops an age and generation-based model of metastatic cancer that reformulates tumor growth and spread using age and generational ancestry, improving numerical stability and interpretability over traditional size-based models.
DOI 10.1016/j.jtbi.2026.112392