Hypocretin receptor 1 blockade early in abstinence reduces future demand for cocaine
Shanna B. Samels, Jessica K. Shaw, I. Pamela Alonso, Emily M. Black, Yanan Zhang, Rodrigo A. España
This study shows that blocking hypocretin receptor 1 early in abstinence reduces cocaine motivation and normalizes dopamine transmission in rats.
Neuropharmacology · Feb 27, 2026Peer-reviewedNeuroscience