Saidi Wang

A systematic study of HIF1A cofactors in hypoxic cancer cells

This study identifies 201 potential HIF1A cofactors in hypoxic cancer cells, with 30 validated and 21 matching known cofactors from public databases.

INSISTC: Incorporating Network Structure Information for Single-Cell Type Classification

INSISTC integrates gene regulatory network structure for single-cell type classification, improving accuracy and providing insights into cell-specific gene regulation.

A revisit to universal single-copy genes in bacterial genomes

The paper re-evaluates universal single-copy genes (USCGs) in bacterial genomes, showing they vary across studies, reliably distinguish species but not strains.

Are known bacterial strains really present?

The paper investigates the reliability of known bacterial strains in shotgun metagenomic samples and finds they are often inconsistent and not supported by coverage data.

A Systematic Evaluation of the Computational Tools for Ligand-receptor-based Cell-Cell Interaction Inference

This study evaluates nine computational tools for predicting ligand-receptor-based cell-cell interactions using mouse single-cell RNA sequencing data.

A computational modeling of primary-microRNA expression

This study models pri-miRNA expression across 1829 cell types and tissues by associating them with mRNAs that reflect their expression patterns.

Hundreds of motif pairs may facilitate enhancer-promoter interactions

The paper identifies hundreds of TF motif pairs that co-occur in enhancer-promoter pairs across seven human cell lines and show their biological relevance.