On the onset of multicellular invasive behavior in hierarchical lineage: the role of inhibitory feedback and local fluctuations
Josué Manik Nava-Sedeño, Abraham Martínez, Haralampos Hatzikirou
This study uses a lattice-gas cellular automaton model to show inhibitory feedback from differentiated cells affects stem cell invasive potential and local fluctuations create slow-moving unstable fronts.
Journal of Theoretical Biology · Jul 26, 2025Peer-reviewedCancer Biology