Author

Mingliang Wang

Nanjing University of Chinese MedicineORCID 0000-0002-4830-9467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:protein structure· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Dan TengiD· 2 shared Kaixian CheniD· 2 shared Mingyue ZhengiD· 2 shared Panpan Shao· 2 shared Sulin ZhangiD· 2 shared Xiaomin LuoiD· 2 shared Xutong LiiD· 2 shared Zhehuan Fan· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Dan TengORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 12, 2026

Functional orthogonality of WRN inhibitor resistance enables alternating therapy and mutation-tolerant inhibitor design in MSI-H cancers

Guizhen Zhou, Dan Teng, Dan Wang…·Mingyue Zheng

This study shows that resistance to different WRN inhibitors in MSI-H cancers creates orthogonal vulnerabilities, enabling alternating therapy and mutation-tolerant inhibitor design.

DOI 10.64898/2026.06.09.731233

humanwhole-exome sequencing

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Molecular BiologybioRxivPreprintJun 4, 2025

Advancing Ligand Binding Affinity Prediction with Cartesian Tensor-Based Deep Learning

Jie Yu, Xia Sheng, Zhehuan Fan…·Mingyue Zheng

PBCNet2.0 predicts protein-ligand binding affinity using a cartesian tensor-based Siamese Neural Network, achieving high accuracy and efficiency compared to physics-based simulations.

2 citations

humanprotein structure

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