Using summary data to detect and quantify ascertainment in biobanks
Babatunde Shittu Olasege, Adrián I. Campos, Julia Sidorenko, Tian Lin, Ciarrah-Jane Shannon Barry, Genona Torruella Maseras, Bjarni Jóhann Vilhjálmsson, Naomi R. Wray, Valentin Hivert, Loïc Yengo
This paper introduces a summary-statistics-based method to detect and quantify ascertainment bias in genetic studies using polygenic scores across multiple biobanks.
bioRxiv · Aug 7, 2026 · PreprintGenetics