BioinformaticsbioRxivPreprint
Deconvolution of Sparse-count RNA Sequencing Data for Tumor Cells Using Embedded Negative Binomial Distributions
Matthew D. Montierth, Hao Yan, Liyang Xie…·Wenyi Wang
The paper develops DeMixNB, a deconvolution model for sparse-count RNA sequencing data, showing its utility in analyzing tumor cell plasticity in breast and lung cancer.
DOI 10.1101/2025.11.21.689822