Targeting PI3K-gamma in myeloid driven tumour immune suppression: A Systematic Review and Meta-Analysis of the Preclinical Literature
Haonan Xu, Shannon Nicole Russell, Katherine Steiner, Eric E. O’Neill, Keaton Ian Jones
This paper reviews preclinical studies on PI3K-gamma inhibition to reverse myeloid-driven immune suppression in solid tumours, finding that combination therapies show greater antitumor effects than monotherapy.
Cancer Immunology Immunotherapy · Aug 6, 2024Peer-reviewedCancer Biology