Bayesian transcriptome-wide association study method leveraging both cis- and trans- eQTL information through summary statistics
Justin M. Luningham, Junyu Chen, Shizhen Tang, Philip L. De Jager, David A. A Bennett, Aron S. Buchman, Jingjing Yang
This paper introduces BGW-TWAS, a Bayesian method for transcriptome-wide association studies that incorporates both cis- and trans-eQTL information, improving power and identifying novel associations with Alzheimer's disease.
The American Journal of Human Genetics · Sep 21, 2020Peer-reviewedGenetics