Author

Laura J. Scott

University of MichiganORCID 0000-0002-5063-3709Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Arushi VarshneyiD· 3 shared Francis S. CollinsiD· 3 shared Jouko SaramiesiD· 3 shared Karen L. MohlkeiD· 3 shared Markku LaaksoiD· 3 shared Michael BoehnkeiD· 3 shared Peter OrchardiD· 3 shared Stephen C.J. ParkeriD· 3 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Arushi VarshneyORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 27, 2026

Erosion of regenerative regulation: age-associated shifts in the skeletal muscle fiber epigenome and transcriptome

Keagan G. Moo, Peter Orchard, Arushi Varshney…·Stephen C.J. Parker

The paper identifies age-associated changes in the skeletal muscle epigenome and transcriptome, revealing shifts in chromatin accessibility and gene expression linked to metabolic and senescence pathways.

DOI 10.64898/2026.08.19.744884

humanscRNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 21, 2026

Integrated Analysis of Skeletal Muscle Transcriptional Networks Characterizes Dysregulation in Pathways and Trait-Associated Regulatory Regions in Type 2 Diabetes

Avery Maddox, Nandini Manickam, Peter Orchard…·Stephen C.J. Parker

The paper identifies dysregulated pathways and candidate driver genes in skeletal muscle from individuals with type 2 diabetes using co-expression networks and single-nucleus RNA-seq data.

DOI 10.64898/2026.08.17.745340

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJun 19, 2026

Donor-matched iPSC model reveals context-dependent T2D genetic signals in fibro-adipogenic progenitors

Christa Ventresca, Arushi Varshney, Peter Orchard…·Stephen C.J. Parker

The paper uses donor-matched iPSC-derived FAPs to show that T2D GWAS signals are enriched in adipogenic FAP subtypes under high-insulin exposure.

DOI 10.64898/2026.02.04.702388

humanscRNA-seq

𝕏 PostBluesky