High burden of premature ventricular contractions upregulates transcriptional markers of inflammation and promotes adverse cardiac remodeling linked to cardiomyopathy
Juana Maria de Lourdes Medina Contreras, Jaime Balderas‐Villalobos, Jose G. Gomez‐Arroyo, Janée Hayles, Károly Kaszala, Alex Y. Tan, Montserrat Samsó, José F. Huizar, José Miguel Eltit
This study shows that high PVC burden causes inflammation and fibrosis, leading to adverse cardiac remodeling and increased risk of heart failure and sudden cardiac death.
Circulation Arrhythmia and Electrophysiology · Jan 1, 2026Peer-reviewedPhysiology