Cancer BiologybioRxivPreprint
Pdk1-dependent metabolic heterogeneity promotes aggressive colorectal cancer through cell-intrinsic interferon signaling
Jessica Calviello, Lisa Pöltl, Alessia Mira…·Carlos Sebastián
This study identifies Pdk1-high metabolic cancer cells in colorectal tumors that drive aggressive behavior through interferon signaling.
DOI 10.64898/2026.10.07.757309