Leif A. Kirsebom

The paper identifies the presence and expression of selenocysteine machinery genes in 40% of mycobacterial genomes and suggests regulatory roles for selC.

The paper shows that loss of ESX-1 genes in M. marinum strain 1218S increases transcription of ESX-6 and LOS genes, affecting colony morphology and biofilm formation.

This study uses whole genome sequencing to reveal extensive genomic diversity among Mycobacterium marinum strains, suggesting they should be divided into two clusters.